Health technology grows exponentially, hence we are generating a sort of science inflation, thus generating more knowledge than we can handle. Medical information duplicates every 5 years. Differently to former years, today we do not have time to keep up to date. This fact explains well why only one out of five decisions is strictly evidence based. At that point, professionals are enabled with real world evidence in order to cope with this trend; it allows us to group collective knowledge, placing mindlines in front of guidelines. Our life is quickly addressing to a digital data economy where massive analysis of big amounts of information gains relevance, hanks to which computers can see and correlate where human mind cannot. We call it big data, a new way of doing science and understanding knowledge, applied to financial markets –in order to predict them-, to social relationships – with sophisticated algorithms for mating-, to everything, and of course, as well to health.